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Year : 2022  |  Volume : 2  |  Issue : 1  |  Page : 35-37

Primary gastric mucosal melanoma: A rare histopathological diagnosis

1 Department of Pathology-Histopathology Division, The Rotherham NHS Foundation Trust, United Kingdom
2 Department of Pathology, Faculty of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Correspondence Address:
Dr. Kafil Akhtar
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aort.aort_3_22

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Primary mucosal melanoma in the gastrointestinal (GI) tract is very rare, as most of the melanomas diagnosed in the GI tract are metastases, secondary to cutaneous melanomas. We report a rare case of primary gastric mucosal melanoma in a 58-year-old male patient who presented with a short history of upper abdominal tightness and pain for 15 days. Upper GI endoscopy revealed a polypoid mucosal mass with ulceration at the gastric antrum of 2 cm × 2 cm dimension, which was diagnosed histopathologically as malignant melanoma. A detailed clinical and laboratory workup did not reveal any other primary site elsewhere and there was no relevant history suggesting a cutaneous melanocytic lesion. Upper GI endoscopy and microscopic tissue examination with immunohistochemistry formed the mainstay of diagnosis of this exceedingly rare neoplasm.

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