Annals of Oncology Research and Therapy

: 2022  |  Volume : 2  |  Issue : 1  |  Page : 1-

Cancer: Plethora of factors

Amal Chandra Kataki 
 Department of Gyaenecological Oncology, Dr. B Borooah Cancer Institute, Guwahati, Assam, India

Correspondence Address:
Dr. Amal Chandra Kataki
Department of Gyaenecological Oncology, Dr. B Borooah Cancer Institute, Guwahati - 781 016, Assam

How to cite this article:
Kataki AC. Cancer: Plethora of factors.Ann Oncol Res Ther 2022;2:1-1

How to cite this URL:
Kataki AC. Cancer: Plethora of factors. Ann Oncol Res Ther [serial online] 2022 [cited 2022 Dec 2 ];2:1-1
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It gives me immense satisfaction as I pen down this Editorial for this issue of Annals of Oncology Research and Therapy. Time is the most valuable asset we all have, and when a reader spends their time on a journal, it in turn should do justice to the time spent by them as well as make ripples, if not waves, of scientific curiosity in the readers' mind. When I gather the feedback, I am proud to say that this Journal has churned a positive impact in a quintessential way.

The aphorism, “An apple a day keeps the doctor away,” originated in Wales, first appearing in a publication in 1866 in a different rhyming format: “Eat an apple on going to bed and you'll keep the doctor from earning his bread.” The saying reappeared in 1913 in its present form. Through the ages, the apple has come to symbolize health and healthy habits and has been used by health organizations to symbolize lifestyle choices that lead to health and wellness.[1]

The incidence of cancer is increasing worldwide. Patterns of cancer are also changing. The plasticity of cancer patterns denotes environmental factors as determinants of cancer and nutrition influences key cellular and molecular processes that characterize cancer.[2] It has been estimated that diet and nutrition could account for 20%–25% of the worldwide cancer burden. The obesogenic effects of a high-calorie diet and lack of physical activity could account for about 10%–15% of the cancer burden, whereas about 5% may be attributable to alcohol and another 5% to specific dietary factors combined. Some nutritional exposures (alcohol and processed meat) are likely causative factors, but no singular factor protects against cancer (except dietary fiber for colorectal cancer). Cancer protection mainly arises from a systemic metabolic environment that promotes healthy cell replication and tissue integrity.[3]

Since ancient times, emphasis on nutrition has been made by our ancestors. The Atharva Veda has mentioned the medicinal value of Indian spices and the significance of good nutrition for building a strong immune system.[4] We live in a fast world where we often ignore the small things which may have a butterfly effect on our overall health. Good nutrition, regular exercise, and a healthy lifestyle should be a part of our daily schedule.

Among the plethora of factors responsible for the causation of cancer, diet and nutrition are modifiable factors. This is a potential advantage that should be capitalized. I congratulate the editorial board, authors, Wolters-Kluwer Medknow, and all well-wishers of this Journal on their commendable endeavor.


1Davis MA, Bynum JP, Sirovich BE. Association between apple consumption and physician visits: Appealing the conventional wisdom that an apple a day keeps the doctor away. JAMA Intern Med 2015;175:777-83.
2Wiseman MJ. Nutrition and cancer: Prevention and survival. Br J Nutr 2019;122:481-7.
3Papadimitriou N, Markozannes G, Kanellopoulou A, Critselis E, Alhardan S, Karafousia V, et al. An umbrella review of the evidence associating diet and cancer risk at 11 anatomical sites. Nat Commun 2021;12:4579.
4Jiang TA. Health benefits of culinary herbs and spices. J AOAC Int 2019;102:395-411.